Difference between revisions of "YBL079W"

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=== Alleles, Strains, and Phenotypes ===
 
[[Category:Topic:Alleles, Strains, and Phenotypes]]
 
==== Complete Deletion ====
 
[[Category:Topic:Alleles, Strains, and Phenotypes:Complete Deletion]]
 
'''Phenotype(s)''': Loss of function (Null) [[Category:Phenotype:Loss of function (Null)]]
 
 
Null mutants display defects in chromosome transmission fidelity and kinetochore integrity <ref name='S000060228'>Kerscher O, et al. (2001) Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics 157(4):1543-53 {{SGDpaper|S000060228}} PMID 11290711</ref> <ref name = 'CAset315-2005-07-29'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=315 Munira Basrai] on 2005-07-29</ref>
 
 
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==Community Commentary==
 
==Community Commentary==

Revision as of 10:51, 24 January 2007

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Systematic name YBL079W
Gene name NUP170
Aliases NLE3
Feature type ORF, Verified
Coordinates Chr II:75256..79764
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Description of YBL079W: Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation, has similarity to Nup157p[1][2][3][4][5]



Community Commentary

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Alleles, Strains, and Phenotypes

Complete Deletion

Phenotype(s): Loss of function (Null)

Null mutants display defects in chromosome transmission fidelity and kinetochore integrity [1] [6]


References

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  1. 1.0 1.1 Kerscher O, et al. (2001) Novel role for a Saccharomyces cerevisiae nucleoporin, Nup170p, in chromosome segregation. Genetics 157(4):1543-53 SGD PMID 11290711
  2. Aitchison JD, et al. (1995) Two novel related yeast nucleoporins Nup170p and Nup157p: complementation with the vertebrate homologue Nup155p and functional interactions with the yeast nuclear pore-membrane protein Pom152p. J Cell Biol 131(5):1133-48 SGD PMID 8522578
  3. Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
  4. Kenna MA, et al. (1996) Yeast N1e3p/Nup170p is required for normal stoichiometry of FG nucleoporins within the nuclear pore complex. Mol Cell Biol 16(5):2025-36 SGD PMID 8628268
  5. Shulga N, et al. (2000) Yeast nucleoporins involved in passive nuclear envelope permeability. J Cell Biol 149(5):1027-38 SGD PMID 10831607
  6. submitted by Munira Basrai on 2005-07-29

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