Difference between revisions of "YJR047C"
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− | '''Description of YJR047C:''' Translation | + | '''Description of YJR047C:''' Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions<ref name='S000040125'>Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 {{SGDpaper|S000040125}} PMID 8314769</ref><ref name='S000045525'>Kang HA, et al. (1993) Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine in Saccharomyces cerevisiae. J Biol Chem 268(20):14750-6 {{SGDpaper|S000045525}} PMID 8325852</ref><ref name='S000045611'>Schnier J, et al. (1991) Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 11(6):3105-14 {{SGDpaper|S000045611}} PMID 1903841</ref><ref name='S000130229'>Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 |
− | {{SGDpaper| | + | {{SGDpaper|S000130229}} PMID 19424157</ref> |
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Revision as of 13:05, 15 May 2009
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Systematic name | YJR047C |
Gene name | ANB1 |
Aliases | HYP1, TIF51B |
Feature type | ORF, Verified |
Coordinates | Chr X:525373..524900 |
Primary SGDID | S000003808 |
Description of YJR047C: Translation elongation factor eIF-5A, previously thought to function in translation initiation; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions[1][2][3][4]
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References
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- ↑ Schwelberger HG, et al. (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25 SGD PMID 8314769
- ↑ Kang HA, et al. (1993) Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine in Saccharomyces cerevisiae. J Biol Chem 268(20):14750-6 SGD PMID 8325852
- ↑ Schnier J, et al. (1991) Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 11(6):3105-14 SGD PMID 1903841
- ↑ Saini P, et al. (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21 SGD PMID 19424157
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