Difference between revisions of "YOR359W"

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'''Description of YOR359W:''' Post-transcriptional gene regulator, RNA-binding protein containing a SAM domain; shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic<ref name='S000114214'>Oberstrass FC, et al. (2006) Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol 13(2):160-7 {{SGDpaper|S000114214}} PMID 16429156</ref><ref name='S000066006'>Dilcher M, et al. (2001) Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6. J Biol Chem 276(37):34537-44
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'''Description of YOR359W:''' Post-transcriptional gene regulator, RNA-binding protein containing a SAM domain; shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic<ref name='S000066006'>Dilcher M, et al. (2001) Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6. J Biol Chem 276(37):34537-44 {{SGDpaper|S000066006}} PMID 11445562</ref><ref name='S000114214'>Oberstrass FC, et al. (2006) Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol 13(2):160-7
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  {{SGDpaper|S000114214}} PMID 16429156</ref>
 
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Revision as of 13:05, 31 March 2009

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Systematic name YOR359W
Gene name VTS1
Aliases
Feature type ORF, Verified
Coordinates Chr XV:1011187..1012758
Primary SGDID S000005886


Description of YOR359W: Post-transcriptional gene regulator, RNA-binding protein containing a SAM domain; shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic[1][2]




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Protein Details

Nucleic Acid Binding

YOR359W binds RNA Specific binding to an RNA stem-loop of CNGGN motif. Involved in CCR4 mediated deadnylation and degradation of targets. [3] [4]





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References

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  1. Dilcher M, et al. (2001) Genetic interactions with the yeast Q-SNARE VTI1 reveal novel functions for the R-SNARE YKT6. J Biol Chem 276(37):34537-44 SGD PMID 11445562
  2. Oberstrass FC, et al. (2006) Shape-specific recognition in the structure of the Vts1p SAM domain with RNA. Nat Struct Mol Biol 13(2):160-7 SGD PMID 16429156
  3. Aviv T, et al. (2003) The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators. Nat Struct Biol 10(8):614-21 SGD PMID 12858164
  4. submitted by Tzvi Aviv on 2003-10-10

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