Difference between revisions of "YOR335C"
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| − | '''Description of YOR335C:''' Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog<ref name='S000046212'>Ripmaster TL, et al. (1995) Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen. Proc Natl Acad Sci U S A 92(11):4932-6 {{SGDpaper|S000046212}} PMID 7761427</ref><ref name='S000040040'>Wrobel C, et al. (1999) CDC64 encodes cytoplasmic alanyl-tRNA synthetase, Ala1p, of Saccharomyces cerevisiae. J Bacteriol 181(24):7618-20 | + | '''Description of YOR335C:''' Cytoplasmic and mitochondrial alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog<ref name='S000079762'>Tang HL, et al. (2004) Translation of a yeast mitochondrial tRNA synthetase initiated at redundant non-AUG codons. J Biol Chem 279(48):49656-63 {{SGDpaper|S000079762}} PMID 15358761</ref><ref name='S000046212'>Ripmaster TL, et al. (1995) Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen. Proc Natl Acad Sci U S A 92(11):4932-6 {{SGDpaper|S000046212}} PMID 7761427</ref><ref name='S000040040'>Wrobel C, et al. (1999) CDC64 encodes cytoplasmic alanyl-tRNA synthetase, Ala1p, of Saccharomyces cerevisiae. J Bacteriol 181(24):7618-20 |
{{SGDpaper|S000040040}} PMID 10601222</ref> | {{SGDpaper|S000040040}} PMID 10601222</ref> | ||
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Revision as of 06:21, 26 February 2009
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| Systematic name | YOR335C |
| Gene name | ALA1 |
| Aliases | CDC64 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:949106..946230 |
| Primary SGDID | S000005862 |
Description of YOR335C: Cytoplasmic and mitochondrial alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog[1][2][3]
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References
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- ↑ Tang HL, et al. (2004) Translation of a yeast mitochondrial tRNA synthetase initiated at redundant non-AUG codons. J Biol Chem 279(48):49656-63 SGD PMID 15358761
- ↑ Ripmaster TL, et al. (1995) Wide cross-species aminoacyl-tRNA synthetase replacement in vivo: yeast cytoplasmic alanine enzyme replaced by human polymyositis serum antigen. Proc Natl Acad Sci U S A 92(11):4932-6 SGD PMID 7761427
- ↑ Wrobel C, et al. (1999) CDC64 encodes cytoplasmic alanyl-tRNA synthetase, Ala1p, of Saccharomyces cerevisiae. J Bacteriol 181(24):7618-20 SGD PMID 10601222
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