Difference between revisions of "YLR396C"

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'''Description of YLR396C:''' ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport<ref name='S000066047'>Peterson MR and Emr SD (2001) The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic 2(7):476-86 {{SGDpaper|S000066047}} PMID 11422941</ref><ref name='S000047466'>Gerhardt B, et al. (1998) The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. J Biol Chem 273(25):15818-29 {{SGDpaper|S000047466}} PMID 9624182</ref><ref name='S000040175'>Seals DF, et al. (2000) A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A 97(17):9402-7
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'''Description of YLR396C:''' ATP-binding protein that is a subunit of the HOPS complex and the CORVET tethering complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport<ref name='S000122612'>Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 {{SGDpaper|S000122612}} PMID 17488625</ref><ref name='S000066047'>Peterson MR and Emr SD (2001) The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic 2(7):476-86 {{SGDpaper|S000066047}} PMID 11422941</ref><ref name='S000047466'>Gerhardt B, et al. (1998) The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. J Biol Chem 273(25):15818-29 {{SGDpaper|S000047466}} PMID 9624182</ref><ref name='S000040175'>Seals DF, et al. (2000) A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A 97(17):9402-7
 
  {{SGDpaper|S000040175}} PMID 10944212</ref>
 
  {{SGDpaper|S000040175}} PMID 10944212</ref>
 
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Revision as of 06:21, 26 February 2009

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Systematic name YLR396C
Gene name VPS33
Aliases CLS14, MET27, PEP14, SLP1, VAM5, VPL25, VPT33
Feature type ORF, Verified
Coordinates Chr XII:912310..910235
Primary SGDID S000004388


Description of YLR396C: ATP-binding protein that is a subunit of the HOPS complex and the CORVET tethering complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport[1][2][3][4]




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References

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  1. Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 SGD PMID 17488625
  2. Peterson MR and Emr SD (2001) The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic 2(7):476-86 SGD PMID 11422941
  3. Gerhardt B, et al. (1998) The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner. J Biol Chem 273(25):15818-29 SGD PMID 9624182
  4. Seals DF, et al. (2000) A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A 97(17):9402-7 SGD PMID 10944212

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