Difference between revisions of "YER007W"

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'''Description of YER007W:''' Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl<ref name='S000039373'>Fleming JA, et al. (2000) Function of tubulin binding proteins in vivo. Genetics 156(1):69-80 {{SGDpaper|S000039373}} PMID 10978276</ref><ref name='S000041301'>Vega LR, et al. (1998) An alpha-tubulin mutant destabilizes the heterodimer: phenotypic consequences and interactions with tubulin-binding proteins. Mol Biol Cell 9(9):2349-60 {{SGDpaper|S000041301}} PMID 9725898</ref><ref name='S000045032'>Hoyt MA, et al. (1997) Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability. Genetics 146(3):849-57 {{SGDpaper|S000045032}} PMID 9215891</ref><ref name='S000058454'>Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24
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'''Description of YER007W:''' Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl<ref name='S000058454'>Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24 {{SGDpaper|S000058454}} PMID 9885248</ref><ref name='S000045032'>Hoyt MA, et al. (1997) Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability. Genetics 146(3):849-57 {{SGDpaper|S000045032}} PMID 9215891</ref><ref name='S000041301'>Vega LR, et al. (1998) An alpha-tubulin mutant destabilizes the heterodimer: phenotypic consequences and interactions with tubulin-binding proteins. Mol Biol Cell 9(9):2349-60 {{SGDpaper|S000041301}} PMID 9725898</ref><ref name='S000039373'>Fleming JA, et al. (2000) Function of tubulin binding proteins in vivo. Genetics 156(1):69-80
  {{SGDpaper|S000058454}} PMID 9885248</ref>
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  {{SGDpaper|S000039373}} PMID 10978276</ref>
 
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Revision as of 14:05, 16 January 2009

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Systematic name YER007W
Gene name PAC2
Aliases
Feature type ORF, Verified
Coordinates Chr V:164526..166082
Primary SGDID S000000809


Description of YER007W: Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl[1][2][3][4]




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References

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  1. Feierbach B, et al. (1999) Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin. J Cell Biol 144(1):113-24 SGD PMID 9885248
  2. Hoyt MA, et al. (1997) Saccharomyces cerevisiae PAC2 functions with CIN1, 2 and 4 in a pathway leading to normal microtubule stability. Genetics 146(3):849-57 SGD PMID 9215891
  3. Vega LR, et al. (1998) An alpha-tubulin mutant destabilizes the heterodimer: phenotypic consequences and interactions with tubulin-binding proteins. Mol Biol Cell 9(9):2349-60 SGD PMID 9725898
  4. Fleming JA, et al. (2000) Function of tubulin binding proteins in vivo. Genetics 156(1):69-80 SGD PMID 10978276

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