Difference between revisions of "YBL052C"

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'''Description of YBL052C:''' Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality<ref name='S000066268'>Howe L, et al. (2001) Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev 15(23):3144-54 {{SGDpaper|S000066268}} PMID 11731478</ref><ref name='S000050029'>John S, et al. (2000) The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev 14(10):1196-208 {{SGDpaper|S000050029}} PMID 10817755</ref><ref name='S000047845'>Reifsnyder C, et al. (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet 14(1):42-9
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'''Description of YBL052C:''' Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality<ref name='S000047845'>Reifsnyder C, et al. (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet 14(1):42-9 {{SGDpaper|S000047845}} PMID 8782818</ref><ref name='S000050029'>John S, et al. (2000) The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev 14(10):1196-208 {{SGDpaper|S000050029}} PMID 10817755</ref><ref name='S000066268'>Howe L, et al. (2001) Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev 15(23):3144-54
  {{SGDpaper|S000047845}} PMID 8782818</ref>
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  {{SGDpaper|S000066268}} PMID 11731478</ref>
 
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Revision as of 03:40, 18 December 2008

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Systematic name YBL052C
Gene name SAS3
Aliases
Feature type ORF, Verified
Coordinates Chr II:121877..119382
Primary SGDID S000000148


Description of YBL052C: Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality[1][2][3]




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References

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  1. Reifsnyder C, et al. (1996) Yeast SAS silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat Genet 14(1):42-9 SGD PMID 8782818
  2. John S, et al. (2000) The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev 14(10):1196-208 SGD PMID 10817755
  3. Howe L, et al. (2001) Histone H3 specific acetyltransferases are essential for cell cycle progression. Genes Dev 15(23):3144-54 SGD PMID 11731478

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