YAL035W
(Redirected from yIF2)
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| Systematic name | YAL035W |
| Gene name | FUN12 |
| Aliases | yIF2 |
| Feature type | ORF, Verified |
| Coordinates | Chr I:76427..79435 |
| Primary SGDID | S000000033 |
Description of YAL035W: GTPase required for general translation initiation; promotes Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; protein abundance increases in response to DNA replication stress; homolog of bacterial IF2[1][2][3]
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References
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- ↑ Choi SK, et al. (1998) Promotion of met-tRNAiMet binding to ribosomes by yIF2, a bacterial IF2 homolog in yeast. Science 280(5370):1757-60 SGD PMID 9624054
- ↑ Lee JH, et al. (2002) Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation. Proc Natl Acad Sci U S A 99(26):16689-94 SGD PMID 12471154
- ↑ Tkach JM, et al. (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.LID - 10.1038/ncb2549 [doi] Nat Cell Biol () SGD PMID 22842922
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