YPR183W

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Systematic name YPR183W
Gene name DPM1
Aliases SED3
Feature type ORF, Verified
Coordinates Chr XVI:900755..901558
Primary SGDID S000006387


Description of YPR183W: Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation[1][2][3][4]




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References

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  1. Albright CF, et al. (1989) A 13-amino acid peptide in three yeast glycosyltransferases may be involved in dolichol recognition. Proc Natl Acad Sci U S A 86(19):7366-9 SGD PMID 2678101
  2. Haselbeck A (1989) Purification of GDP mannose:dolichyl-phosphate O-beta-D-mannosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 181(3):663-8 SGD PMID 2659345
  3. Orlean P (1990) Dolichol phosphate mannose synthase is required in vivo for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and N glycosylation of protein in Saccharomyces cerevisiae. Mol Cell Biol 10(11):5796-805 SGD PMID 2146492
  4. Orlean P, et al. (1988) Cloning and sequencing of the yeast gene for dolichol phosphate mannose synthase, an essential protein. J Biol Chem 263(33):17499-507 SGD PMID 3053713

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