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Systematic name YPR057W
Gene name BRR1
Feature type ORF, Verified
Coordinates Chr XVI:672471..673496
Primary SGDID S000006261

Description of YPR057W: snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed[1][2][3]


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  1. Liu Q, et al. (1997) The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell 90(6):1013-21 SGD PMID 9323129
  2. Noble SM and Guthrie C (1996) Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations. Genetics 143(1):67-80 SGD PMID 8722763
  3. Noble SM and Guthrie C (1996) Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs. EMBO J 15(16):4368-79 SGD PMID 8861964

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