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Systematic name YPL256C
Gene name CLN2
Feature type ORF, Verified
Coordinates Chr XVI:66614..64977
Primary SGDID S000006177

Description of YPL256C: G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)[1][2][3][4]


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  1. Cross FR, et al. (1994) Role of Swi4 in cell cycle regulation of CLN2 expression. Mol Cell Biol 14(7):4779-87 SGD PMID 8007977
  2. Hadwiger JA, et al. (1989) A family of cyclin homologs that control the G1 phase in yeast. Proc Natl Acad Sci U S A 86(16):6255-9 SGD PMID 2569741
  3. Stuart D and Wittenberg C (1994) Cell cycle-dependent transcription of CLN2 is conferred by multiple distinct cis-acting regulatory elements. Mol Cell Biol 14(7):4788-801 SGD PMID 8007978
  4. Wittenberg C, et al. (1990) G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase. Cell 62(2):225-37 SGD PMID 2142620

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