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Systematic name YPL241C
Gene name CIN2
Feature type ORF, Verified
Coordinates Chr XVI:96258..95372
Primary SGDID S000006162

Description of YPL241C: GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; deletion complemented by human GAP, retinitis pigmentosa 2[1][2][3][4]


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  1. Hoyt MA, et al. (1990) Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes. Mol Cell Biol 10(1):223-34 SGD PMID 2403635
  2. Stearns T, et al. (1990) Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function. Genetics 124(2):251-62 SGD PMID 2407611
  3. Tian G, et al. (1996) Pathway leading to correctly folded beta-tubulin. Cell 86(2):287-96 SGD PMID 8706133
  4. Veltel S, et al. (2008) The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3. Nat Struct Mol Biol 15(4):373-80 SGD PMID 18376416

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