YPL167C

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Systematic name YPL167C
Gene name REV3
Aliases PSO1
Feature type ORF, Verified
Coordinates Chr XVI:237107..232593
Primary SGDID S000006088


Description of YPL167C: Catalytic subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair[1][2][3]




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References

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  1. Kolas NK and Durocher D (2006) DNA repair: DNA polymerase zeta and Rev1 break in. Curr Biol 16(8):R296-9 SGD PMID 16631579
  2. Lee KY and Myung K (2008) PCNA Modifications for Regulation of Post-Replication Repair Pathways. Mol Cells 26(1):5-11 SGD PMID 18525240
  3. Prakash S, et al. (2005) Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu Rev Biochem 74:317-53 SGD PMID 15952890

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