YPL140C

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Systematic name YPL140C
Gene name MKK2
Aliases LPI6, SSP33
Feature type ORF, Verified
Coordinates Chr XVI:289034..287514
Primary SGDID S000006061


Description of YPL140C: Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p[1][2][3][4]




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References

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  1. Heinisch JJ, et al. (1999) The protein kinase C-mediated MAP kinase pathway involved in the maintenance of cellular integrity in Saccharomyces cerevisiae. Mol Microbiol 32(4):671-80 SGD PMID 10361272
  2. Irie K, et al. (1993) MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C. Mol Cell Biol 13(5):3076-83 SGD PMID 8386320
  3. Levin DE, et al. (1994) Dissecting the protein kinase C/MAP kinase signalling pathway of Saccharomyces cerevisiae. Cell Mol Biol Res 40(3):229-39 SGD PMID 7874200
  4. Soler M, et al. (1995) Characterization of domains in the yeast MAP kinase Slt2 (Mpk1) required for functional activity and in vivo interaction with protein kinases Mkk1 and Mkk2. Mol Microbiol 17(5):833-42 SGD PMID 8596433

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