YPL065W

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Systematic name YPL065W
Gene name VPS28
Aliases VPL13, VPT28
Feature type ORF, Verified
Coordinates Chr XVI:427927..428655
Primary SGDID S000005986


Description of YPL065W: Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, and Mvb12p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p[1][2]




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References

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  1. Katzmann DJ, et al. (2001) Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell 106(2):145-55 SGD PMID 11511343
  2. Pineda-Molina E, et al. (2006) The crystal structure of the C-terminal domain of Vps28 reveals a conserved surface required for Vps20 recruitment. Traffic 7(8):1007-16 SGD PMID 16749904

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