YPL063W
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| Systematic name | YPL063W |
| Gene name | TIM50 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:429939..431369 |
| Primary SGDID | S000005984 |
Description of YPL063W: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); acts as receptor for the TIM23 complex guiding incoming precursors from the TOM complex; may control the gating of the Tim23p-Tim17p channel[1][2][3][4]
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Protein Details
Protein Localization
Protein identified in a purified mitochondrial extract. [5] [6]
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References
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- ↑ Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 SGD PMID 15797382
- ↑ Gevorkyan-Airapetov L, et al. (2009) Interaction of Tim23 with Tim50 Is Essential for Protein Translocation by the Mitochondrial TIM23 Complex. J Biol Chem 284(8):4865-72 SGD PMID 19017642
- ↑ Meinecke M, et al. (2006) Tim50 maintains the permeability barrier of the mitochondrial inner membrane. Science 312(5779):1523-6 SGD PMID 16763150
- ↑ Mokranjac D, et al. (2009) Role of Tim50 in the transfer of precursor proteins from the outer to the inner membrane of mitochondria. Mol Biol Cell 20(5):1400-7 SGD PMID 19144822
- ↑ Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
- ↑ submitted by Steffen Ohlmeier on 2004-04-08
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