YPL036W

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Systematic name YPL036W
Gene name PMA2
Aliases
Feature type ORF, Verified
Coordinates Chr XVI:482843..485686
Primary SGDID S000005957


Description of YPL036W: Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential[1][2]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]


Other

Expression pattern

PMA2 is a plasma membrane ATPase with negligable expression under all conditions, as compared to the PMA1 isoform. Both isoforms increase in expression under respiratory metabolism, in comparison to fermentative. In diauxic growth PMA2 also increases in expression during the transition to stationary phase after ethanol depletion. The authors suggest that the PMA2 isoform may play a role in metabolism during carbon starvation. [5] [6]





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References

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  1. Schlesser A, et al. (1988) A second transport ATPase gene in Saccharomyces cerevisiae. J Biol Chem 263(36):19480-7 SGD PMID 2904437
  2. Supply P, et al. (1993) Enzymatic properties of the PMA2 plasma membrane-bound H(+)-ATPase of Saccharomyces cerevisiae. J Biol Chem 268(26):19753-9 SGD PMID 8396147
  3. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. submitted by Viktor Boer on 2003-07-25
  5. Fernandes AR and Sa-Correia I (2003) Transcription patterns of PMA1 and PMA2 genes and activity of plasma membrane H+-ATPase in Saccharomyces cerevisiae during diauxic growth and stationary phase. Yeast 20(3):207-19 SGD PMID 12557274
  6. submitted by Matthew Brauer on 2003-08-29

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