YOR324C

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Systematic name YOR324C
Gene name FRT1
Aliases HPH1
Feature type ORF, Verified
Coordinates Chr XV:925040..923232
Primary SGDID S000005851


Description of YOR324C: Tail-anchored ER membrane protein of unknown function; substrate of the phosphatase calcineurin; interacts with homolog Frt2p; promotes cell growth in stress conditions, possibly via a role in posttranslational translocation; FRT1 has a paralog, FRT2, that arose from the whole genome duplication[1][2][3][4]




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References

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  1. Burri L and Lithgow T (2004) A complete set of SNAREs in yeast. Traffic 5(1):45-52 SGD PMID 14675424
  2. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  3. Heath VL, et al. (2004) Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Eukaryot Cell 3(3):695-704 SGD PMID 15189990
  4. Pina FJ, et al. (2011) Hph1 and hph2 are novel components of the sec63/sec62 posttranslational translocation complex that aid in vacuolar proton ATPase biogenesis. Eukaryot Cell 10(1):63-71 SGD PMID 21097665

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