YOR251C
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| Systematic name | YOR251C |
| Gene name | TUM1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:803464..802550 |
| Primary SGDID | S000005777 |
Description of YOR251C: Rhodanese domain sulfur transferase, accepts persulfite from Nfs1p and transfers it to Uba4p in the pathway for 2-thiolation of the wobble uridine base of tRNAs; also stimulates sulfur transfer by Nfs1p; may be mitochondrially localized[1][2][3][4][5]
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References
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- ↑ Dubaquie Y, et al. (1998) Identification of in vivo substrates of the yeast mitochondrial chaperonins reveals overlapping but non-identical requirement for hsp60 and hsp10. EMBO J 17(20):5868-76 SGD PMID 9774331
- ↑ Huang B, et al. (2008) A genome-wide screen identifies genes required for formation of the wobble nucleoside 5-methoxycarbonylmethyl-2-thiouridine in Saccharomyces cerevisiae. RNA 14(10):2183-94 SGD PMID 18755837
- ↑ Leidel S, et al. (2009) Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA. Nature 458(7235):228-32 SGD PMID 19145231
- ↑ Noma A, et al. (2009) Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions. Nucleic Acids Res 37(4):1335-52 SGD PMID 19151091
- ↑ Poirey R and Jauniaux JC (1997) Sequencing analysis of a 36.8 kb fragment of yeast chromosome XV reveals 26 open reading frames including SEC63, CDC31, SUG2, GCD1, RBL2, PNT1, PAC1 and VPH1. Yeast 13(5):483-7 SGD PMID 9153759
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