YOR164C

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Systematic name YOR164C
Gene name GET4
Aliases ENV8
Feature type ORF, Verified
Coordinates Chr XV:644332..643394
Primary SGDID S000005690


Description of YOR164C: Protein with a role in insertion of tail-anchored proteins into the ER membrane; forms a complex with Mdy2p; highly conserved across species and homologous to human gene C7orf20[1][2][3][4]




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References

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  1. Chang YW, et al. (2010) Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1. J Biol Chem 285(13):9962-70 SGD PMID 20106980
  2. Fernandes JM, et al. (2008) Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development. Genomics 91(4):315-25 SGD PMID 18249086
  3. Fleischer TC, et al. (2006) Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev 20(10):1294-307 SGD PMID 16702403
  4. Jonikas MC, et al. (2009) Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323(5922):1693-7 SGD PMID 19325107

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