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Systematic name YOR157C
Gene name PUP1
Feature type ORF, Verified
Coordinates Chr XV:631751..630966
Primary SGDID S000005683

Description of YOR157C: Beta 2 subunit of the 20S proteasome; endopeptidase with trypsin-like activity that cleaves after basic residues; synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z[1][2][3]


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  1. Groll M, et al. (1997) Structure of 20S proteasome from yeast at 2.4 A resolution. Nature 386(6624):463-71 SGD PMID 9087403
  2. Jager S, et al. (1999) Proteasome beta-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function. J Mol Biol 291(4):997-1013 SGD PMID 10452902
  3. Nussbaum AK, et al. (1998) Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. Proc Natl Acad Sci U S A 95(21):12504-9 SGD PMID 9770515

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