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Systematic name YOR070C
Gene name GYP1
Aliases YOR29-21
Feature type ORF, Verified
Coordinates Chr XV:457820..455907
Primary SGDID S000005596

Description of YOR070C: Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion[1][2][3][4][5]


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  1. Albert S, et al. (1999) Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases. EMBO J 18(19):5216-25 SGD PMID 10508155
  2. Du LL and Novick P (2001) Yeast rab GTPase-activating protein Gyp1p localizes to the Golgi apparatus and is a negative regulator of Ypt1p. Mol Biol Cell 12(5):1215-26 SGD PMID 11359917
  3. Du LL, et al. (1998) Identification of a Sec4p GTPase-activating protein (GAP) as a novel member of a Rab GAP family. J Biol Chem 273(6):3253-6 SGD PMID 9452439
  4. Jones S, et al. (1998) Identification of regulators for Ypt1 GTPase nucleotide cycling. Mol Biol Cell 9(10):2819-37 SGD PMID 9763446
  5. Wang L, et al. (2003) Hierarchy of protein assembly at the vertex ring domain for yeast vacuole docking and fusion. J Cell Biol 160(3):365-74 SGD PMID 12566429

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