YOR064C

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Systematic name YOR064C
Gene name YNG1
Aliases YOR29-15
Feature type ORF, Verified
Coordinates Chr XV:446738..446079
Primary SGDID S000005590


Description of YOR064C: Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1[1][2][3][4]




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References

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  1. Howe L, et al. (2002) Yng1p modulates the activity of Sas3p as a component of the yeast NuA3 Hhistone acetyltransferase complex. Mol Cell Biol 22(14):5047-53 SGD PMID 12077334
  2. Loewith R, et al. (2000) Three yeast proteins related to the human candidate tumor suppressor p33(ING1) are associated with histone acetyltransferase activities. Mol Cell Biol 20(11):3807-16 SGD PMID 10805724
  3. Martin DG, et al. (2006) The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3. Mol Cell Biol 26(21):7871-9 SGD PMID 16923967
  4. Taverna SD, et al. (2006) Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell 24(5):785-96 SGD PMID 17157260

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