YOR036W

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Systematic name YOR036W
Gene name PEP12
Aliases VPL6, VPS6, VPT13
Feature type ORF, Verified
Coordinates Chr XV:400348..401214
Primary SGDID S000005562


Description of YOR036W: Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin[1][2][3][4]




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References

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  1. Bassham DC, et al. (1995) An Arabidopsis syntaxin homologue isolated by functional complementation of a yeast pep12 mutant. Proc Natl Acad Sci U S A 92(16):7262-6 SGD PMID 7638178
  2. Becherer KA, et al. (1996) Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast. Mol Biol Cell 7(4):579-94 SGD PMID 8730101
  3. Gerrard SR, et al. (2000) Pep12p is a multifunctional yeast syntaxin that controls entry of biosynthetic, endocytic and retrograde traffic into the prevacuolar compartment. Traffic 1(3):259-69 SGD PMID 11208109
  4. Gotte M and Gallwitz D (1997) High expression of the yeast syntaxin-related Vam3 protein suppresses the protein transport defects of a pep12 null mutant. FEBS Lett 411(1):48-52 SGD PMID 9247140

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