From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YOL020W
Gene name TAT2
Aliases LTG3, SAB2, SCM2, TAP2
Feature type ORF, Verified
Coordinates Chr XV:286172..287950
Primary SGDID S000005380

Description of YOL020W: High affinity tryptophan and tyrosine permease, overexpression confers FK506 and FTY720 resistance[1][2][3][4]


Community Commentary

About Community Commentary. Please share your knowledge!



See Help:References on how to add references

  1. Heitman J, et al. (1993) The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae. Mol Cell Biol 13(8):5010-9 SGD PMID 7687745
  2. Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 SGD PMID 10654085
  3. Schmidt A, et al. (1994) Two FK506 resistance-conferring genes in Saccharomyces cerevisiae, TAT1 and TAT2, encode amino acid permeases mediating tyrosine and tryptophan uptake. Mol Cell Biol 14(10):6597-606 SGD PMID 7523855
  4. Welsch CA, et al. (2003) Ubiquitin pathway proteins influence the mechanism of action of the novel immunosuppressive drug FTY720 in Saccharomyces cerevisiae. J Biol Chem 278(29):26976-82 SGD PMID 12709439

See Help:Categories on how to add the wiki page for this gene to a Category </protect>