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Systematic name YNR052C
Gene name POP2
Aliases CAF1
Feature type ORF, Verified
Coordinates Chr XIV:720647..719346
Primary SGDID S000005335

Description of YNR052C: RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation[1][2][3]


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  1. Daugeron MC, et al. (2001) The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation. Nucleic Acids Res 29(12):2448-55 SGD PMID 11410650
  2. Thore S, et al. (2003) X-ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex. EMBO Rep 4(12):1150-5 SGD PMID 14618157
  3. Tucker M, et al. (2002) Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae. EMBO J 21(6):1427-36 SGD PMID 11889048

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