YNR032C-A

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Systematic name YNR032C-A
Gene name HUB1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:687464..687243
Primary SGDID S000007251


Description of YNR032C-A: Ubiquitin-like protein modifier; promotes alternative splicing of SRC1 pre-mRNA; binds non-covalently to the HIND domain of Snu66, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [5] [6]





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References

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  1. Dittmar GA, et al. (2002) Role of a ubiquitin-like modification in polarized morphogenesis. Science 295(5564):2442-6 SGD PMID 11923536
  2. Luders J, et al. (2003) The ubiquitin-like protein HUB1 forms SDS-resistant complexes with cellular proteins in the absence of ATP. EMBO Rep 4(12):1169-74 SGD PMID 14608371
  3. McNally T, et al. (2003) Structural analysis of UBL5, a novel ubiquitin-like modifier. Protein Sci 12(7):1562-6 SGD PMID 12824502
  4. Mishra SK, et al. (2011) Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing. Nature () SGD PMID 21614000
  5. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. submitted by Viktor Boer on 2003-08-06

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