YNR001C

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Systematic name YNR001C
Gene name CIT1
Aliases CS1, LYS6
Feature type ORF, Verified
Coordinates Chr XIV:631061..629622
Primary SGDID S000005284


Description of YNR001C: Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein[1][2]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [3] [4]





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References

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  1. Kim KS, et al. (1986) Saccharomyces cerevisiae contains two functional citrate synthase genes. Mol Cell Biol 6(6):1936-42 SGD PMID 3023912
  2. Suissa M, et al. (1984) Isolation of the nuclear yeast genes for citrate synthase and fifteen other mitochondrial proteins by a new screening method. EMBO J 3(8):1773-81 SGD PMID 6090126
  3. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  4. submitted by Steffen Ohlmeier on 2004-04-08

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