YNL310C

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Systematic name YNL310C
Gene name ZIM17
Aliases FMP28, HEP1, TIM15
Feature type ORF, Verified
Coordinates Chr XIV:52431..51907
Primary SGDID S000005254


Description of YNL310C: Heat shock protein with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix[1][2][3]




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References

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  1. Burri L, et al. (2004) Zim17, a novel zinc finger protein essential for protein import into mitochondria. J Biol Chem 279(48):50243-9 SGD PMID 15383543
  2. Sanjuan Szklarz LK, et al. (2005) Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis. J Mol Biol 351(1):206-18 SGD PMID 15992824
  3. Sichting M, et al. (2005) Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1. EMBO J 24(5):1046-56 SGD PMID 15719019

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