YNL189W
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| Systematic name | YNL189W |
| Gene name | SRP1 |
| Aliases | KAP60, SCM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:284260..285888 |
| Primary SGDID | S000005133 |
Description of YNL189W: Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation[1][2]
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References
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- ↑ Enenkel C, et al. (1995) Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J Biol Chem 270(28):16499-502 SGD PMID 7622450
- ↑ Tabb MM, et al. (2000) Evidence for separable functions of Srp1p, the yeast homolog of importin alpha (Karyopherin alpha): role for Srp1p and Sts1p in protein degradation. Mol Cell Biol 20(16):6062-73 SGD PMID 10913188
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