YNL187W

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Systematic name YNL187W
Gene name SWT21
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:287994..289067
Primary SGDID S000005131


Description of YNL187W: Protein involved in mRNA splicing; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; interacts genetically with Prp40p and Tgs1p; contains WD40 repeats[1][2][3]




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References

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  1. Hage R, et al. (2009) A targeted bypass screen identifies Ynl187p, Prp42p, Snu71p, and Cbp80p for stable U1 snRNP/Pre-mRNA interaction. Mol Cell Biol 29(14):3941-52 SGD PMID 19451230
  2. Hausmann S, et al. (2008) Genetic and Biochemical Analysis of Yeast and Human Cap Trimethylguanosine Synthase: FUNCTIONAL OVERLAP OF 2,2,7-TRIMETHYLGUANOSINE CAPS, SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENTS, PRE-mRNA SPLICING FACTORS, AND RNA DECAY PATHWAYS. J Biol Chem 283(46):31706-18 SGD PMID 18775984
  3. Murphy MW, et al. (2004) The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing. Genetics 166(1):53-65 SGD PMID 15020406

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