YNL139C
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| Systematic name | YNL139C |
| Gene name | THO2 |
| Aliases | LDB5, RLR1, ZRG13 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:365717..360924 |
| Primary SGDID | S000005083 |
Description of YNL139C: Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids[1][2][3][4]
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References
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- ↑ Chavez S, et al. (2000) A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae. EMBO J 19(21):5824-34 SGD PMID 11060033
- ↑ Piruat JI and Aguilera A (1998) A novel yeast gene, THO2, is involved in RNA pol II transcription and provides new evidence for transcriptional elongation-associated recombination. EMBO J 17(16):4859-72 SGD PMID 9707445
- ↑ Rondon AG, et al. (2003) Molecular evidence that the eukaryotic THO/TREX complex is required for efficient transcription elongation. J Biol Chem 278(40):39037-43 SGD PMID 12871933
- ↑ West RW Jr, et al. (2000) RLR1 (THO2), required for expressing lacZ fusions in yeast, is conserved from yeast to humans and is a suppressor of SIN4. Gene 243(1-2):195-205 SGD PMID 10675628
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