YNL026W
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| Systematic name | YNL026W |
| Gene name | SAM50 |
| Aliases | OMP85, TOB55 |
| Feature type | ORF, Verified |
| Coordinates | Chr XIV:581920..583374 |
| Primary SGDID | S000004971 |
Description of YNL026W: Essential component of the Sorting and Assembly Machinery (SAM or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; homologous to bacterial Omp85[1][2][3][4]
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References
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- ↑ Gentle I, et al. (2004) The Omp85 family of proteins is essential for outer membrane biogenesis in mitochondria and bacteria. J Cell Biol 164(1):19-24 SGD PMID 14699090
- ↑ Habib SJ, et al. (2005) Assembly of the TOB complex of mitochondria. J Biol Chem 280(8):6434-40 SGD PMID 15590639
- ↑ Kozjak V, et al. (2003) An essential role of Sam50 in the protein sorting and assembly machinery of the mitochondrial outer membrane. J Biol Chem 278(49):48520-3 SGD PMID 14570913
- ↑ Paschen SA, et al. (2003) Evolutionary conservation of biogenesis of beta-barrel membrane proteins. Nature 426(6968):862-6 SGD PMID 14685243
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