YMR308C

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Systematic name YMR308C
Gene name PSE1
Aliases KAP121
Feature type ORF, Verified
Coordinates Chr XIII:892221..888952
Primary SGDID S000004925


Description of YMR308C: Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p[1][2][3][4][5][6]




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References

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  1. Delahodde A, et al. (2001) Pse1/Kap121-dependent nuclear localization of the major yeast multidrug resistance (MDR) transcription factor Pdr1. Mol Microbiol 39(2):304-12 SGD PMID 11136452
  2. Isoyama T, et al. (2001) Nuclear import of the yeast AP-1-like transcription factor Yap1p is mediated by transport receptor Pse1p, and this import step is not affected by oxidative stress. J Biol Chem 276(24):21863-9 SGD PMID 11274141
  3. Leslie DM, et al. (2002) Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast. Mol Cell Biol 22(8):2544-55 SGD PMID 11909949
  4. Marelli M, et al. (1998) Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p. J Cell Biol 143(7):1813-30 SGD PMID 9864357
  5. Seedorf M and Silver PA (1997) Importin/karyopherin protein family members required for mRNA export from the nucleus. Proc Natl Acad Sci U S A 94(16):8590-5 SGD PMID 9238021
  6. Ueta R, et al. (2003) Pse1p mediates the nuclear import of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae. J Biol Chem 278(50):50120-7 SGD PMID 14523005

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