YMR258C

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Systematic name YMR258C
Gene name ROY1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:784281..782620
Primary SGDID S000004871


Description of YMR258C: GTPase inhibitor with similarity to F-box proteins; inhibits Ypt52p GTPase activity by preventing Ypt52p from binding GTP; involved in regulating intracellular trafficking; physically interacts with Skp1p[1][2][3]




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References

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  1. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
  2. Liu Y, et al. (2011) Non-SCF-type F-box protein Roy1/Ymr258c interacts with a Rab5-like GTPase Ypt52 and inhibits Ypt52 function. Mol Biol Cell 22(9):1575-84 SGD PMID 21389113
  3. Seol JH, et al. (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol 3(4):384-91 SGD PMID 11283612

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