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Systematic name YMR239C
Gene name RNT1
Feature type ORF, Verified
Coordinates Chr XIII:749677..748262
Primary SGDID S000004852

Description of YMR239C: RNAase III; involved in rDNA transcription and rRNA processing; also cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end; involved in polyadenylation-independent transcription termination[1][2][3][4]


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  1. Abou Elela S and Ares M Jr (1998) Depletion of yeast RNase III blocks correct U2 3' end formation and results in polyadenylated but functional U2 snRNA. EMBO J 17(13):3738-46 SGD PMID 9649443
  2. Catala M, et al. (2008) Deletion of Rnt1p alters the proportion of open versus closed rRNA gene repeats in yeast. Mol Cell Biol 28(2):619-29 SGD PMID 17991894
  3. Elela SA, et al. (1996) RNase III cleaves eukaryotic preribosomal RNA at a U3 snoRNP-dependent site. Cell 85(1):115-24 SGD PMID 8620530
  4. Ghazal G, et al. (2009) Yeast RNase III triggers polyadenylation-independent transcription termination. Mol Cell 36(1):99-109 SGD PMID 19818713

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