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Systematic name YMR234W
Gene name RNH1
Feature type ORF, Verified
Coordinates Chr XIII:740266..741312
Primary SGDID S000004847

Description of YMR234W: Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I; the homolog of mammalian RNAse HII (the S. cerevisiae homolog of mammalian RNAse HI is RNH201)[1][2][3]


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  1. Cerritelli SM and Crouch RJ (1995) The non-RNase H domain of Saccharomyces cerevisiae RNase H1 binds double-stranded RNA: magnesium modulates the switch between double-stranded RNA binding and RNase H activity. RNA 1(3):246-59 SGD PMID 7489497
  2. Huet J, et al. (1977) Characterization of ribonuclease H activity associated yeast RNA polymerase A. J Biol Chem 252(24):8848-55 SGD PMID 21884
  3. Itaya M, et al. (1991) Selective cloning of genes encoding RNase H from Salmonella typhimurium, Saccharomyces cerevisiae and Escherichia coli rnh mutant. Mol Gen Genet 227(3):438-45 SGD PMID 1650910

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