YMR192W

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Systematic name YMR192W
Gene name GYL1
Aliases APP2
Feature type ORF, Verified
Coordinates Chr XIII:647118..649280
Primary SGDID S000004804


Description of YMR192W: Putative GTPase activating protein (GAP) with a role in exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth[1][2][3][4][5]




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References

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  1. Bon E, et al. (2000) A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Yeast 16(13):1229-41 SGD PMID 10992286
  2. Chesneau L, et al. (2004) Gyp5p and Gyl1p are involved in the control of polarized exocytosis in budding yeast. J Cell Sci 117(Pt 20):4757-67 SGD PMID 15331637
  3. Friesen H, et al. (2005) Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking. Genetics 170(2):555-68 SGD PMID 15802519
  4. Prigent M, et al. (2011) The RabGAP proteins Gyp5p and Gyl1p recruit the BAR domain protein Rvs167p for polarized exocytosis.LID - 10.1111/j.1600-0854.2011.01218.x [doi] Traffic () SGD PMID 21554509
  5. Samanta MP and Liang S (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83 SGD PMID 14566057

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