YMR139W

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Systematic name YMR139W
Gene name RIM11
Aliases GSK3, MDS1
Feature type ORF, Verified
Coordinates Chr XIII:546125..547237
Primary SGDID S000004747


Description of YMR139W: Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta[1][2][3]




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References

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  1. Malathi K, et al. (1997) Interaction of yeast repressor-activator protein Ume6p with glycogen synthase kinase 3 homolog Rim11p. Mol Cell Biol 17(12):7230-6 SGD PMID 9372955
  2. Puziss JW, et al. (1994) MDS1, a dosage suppressor of an mck1 mutant, encodes a putative yeast homolog of glycogen synthase kinase 3. Mol Cell Biol 14(1):831-9 SGD PMID 8264650
  3. Rubin-Bejerano I, et al. (2004) The in vivo activity of Ime1, the key transcriptional activator of meiosis-specific genes in Saccharomyces cerevisiae, is inhibited by the cyclic AMP/protein kinase A signal pathway through the glycogen synthase kinase 3-beta homolog Rim11. Mol Cell Biol 24(16):6967-79 SGD PMID 15282298

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