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Systematic name YMR074C
Gene name
Feature type ORF, Verified
Coordinates Chr XIII:413473..413036
Primary SGDID S000004678

Description of YMR074C: Protein with homology to human PDCD5, which is involved in programmed cell death; N-terminal region forms a conserved triple-helix bundle structure; overexpression promotes H2O2-induced apoptosis; YMR074C is not an essential gene[1][2][3]


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  1. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
  2. Hong J, et al. (2009) Solution structure of S. cerevisiae PDCD5-like protein and its promoting role in H(2)O(2)-induced apoptosis in yeast. Biochemistry 48(29):6824-34 SGD PMID 19469552
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095

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