YMR009W

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Systematic name YMR009W
Gene name ADI1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:284102..284641
Primary SGDID S000004611


Description of YMR009W: Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions[1][2]




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References

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  1. Hirano W, et al. (2005) Membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1 (MTCBP-1) acts as an eukaryotic aci-reductone dioxygenase (ARD) in the methionine salvage pathway. Genes Cells 10(6):565-74 SGD PMID 15938715
  2. Zer C and Chanfreau G (2005) Regulation and surveillance of normal and 3'-extended forms of the yeast aci-reductone dioxygenase mRNA by RNase III cleavage and exonucleolytic degradation. J Biol Chem 280(32):28997-9003 SGD PMID 15967792

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