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Systematic name YML031W
Gene name NDC1
Feature type ORF, Verified
Coordinates Chr XIII:214189..216156
Primary SGDID S000004493

Description of YML031W: Subunit of the transmembrane ring of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport, NPC biogenesis and spindle pole body duplication; homologous to human NDC1[1][2][3][4][5][6]


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  1. Chial HJ, et al. (1999) Altered dosage of the Saccharomyces cerevisiae spindle pole body duplication gene, NDC1, leads to aneuploidy and polyploidy. Proc Natl Acad Sci U S A 96(18):10200-5 SGD PMID 10468586
  2. Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 SGD PMID 19524430
  3. Lau CK, et al. (2004) A novel allele of Saccharomyces cerevisiae NDC1 reveals a potential role for the spindle pole body component Ndc1p in nuclear pore assembly. Eukaryot Cell 3(2):447-58 SGD PMID 15075274
  4. Onischenko E, et al. (2009) Role of the Ndc1 interaction network in yeast nuclear pore complex assembly and maintenance. J Cell Biol 185(3):475-91 SGD PMID 19414609
  5. Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
  6. Thomas JH and Botstein D (1986) A gene required for the separation of chromosomes on the spindle apparatus in yeast. Cell 44(1):65-76 SGD PMID 3510081

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