YLR292C

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Systematic name YLR292C
Gene name SEC72
Aliases SEC67, SIM2
Feature type ORF, Verified
Coordinates Chr XII:720370..719789
Primary SGDID S000004283


Description of YLR292C: Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER[1]




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Community Commentary

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Interactions

Two Hybrid

Two Hybrid interaction with YLR301w
[2] [3]





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References

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  1. Young BP, et al. (2001) Sec63p and Kar2p are required for the translocation of SRP-dependent precursors into the yeast endoplasmic reticulum in vivo. EMBO J 20(1-2):262-71 SGD PMID 11226176
  2. Willer M, et al. (2003) Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane. Yeast 20(2):133-48 SGD PMID 12518317
  3. submitted by Colin Stirling on 2003-02-05

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