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Systematic name YLR272C
Gene name YCS4
Aliases LOC7
Feature type ORF, Verified
Coordinates Chr XII:687202..683672
Primary SGDID S000004262

Description of YLR272C: Subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin, tRNA gene clustering at the nucleolus, and silencing at the mating type locus[1][2][3][4][5]


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  1. Bhalla N, et al. (2002) Mutation of YCS4, a budding yeast condensin subunit, affects mitotic and nonmitotic chromosome behavior. Mol Biol Cell 13(2):632-45 SGD PMID 11854418
  2. Biggins S, et al. (2001) Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics 159(2):453-70 SGD PMID 11606525
  3. Freeman L, et al. (2000) The condensin complex governs chromosome condensation and mitotic transmission of rDNA. J Cell Biol 149(4):811-24 SGD PMID 10811823
  4. Haeusler RA, et al. (2008) Clustering of yeast tRNA genes is mediated by specific association of condensin with tRNA gene transcription complexes. Genes Dev 22(16):2204-14 SGD PMID 18708579
  5. Lavoie BD, et al. (2002) In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin. J Cell Biol 156(5):805-15 SGD PMID 11864994

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