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Systematic name YLR258W
Gene name GSY2
Feature type ORF, Verified
Coordinates Chr XII:660716..662833
Primary SGDID S000004248

Description of YLR258W: Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase[1][2][3][4][5][6][7][8]


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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [9] [10]



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  1. Farkas I, et al. (1991) Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled. J Biol Chem 266(24):15602-7 SGD PMID 1908457
  2. Hardy TA and Roach PJ (1993) Control of yeast glycogen synthase-2 by COOH-terminal phosphorylation. J Biol Chem 268(32):23799-805 SGD PMID 8226915
  3. Hardy TA, et al. (1994) Interactions between cAMP-dependent and SNF1 protein kinases in the control of glycogen accumulation in Saccharomyces cerevisiae. J Biol Chem 269(45):27907-13 SGD PMID 7961723
  4. Huang D, et al. (1998) Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: control of glycogen biosynthesis by Pcl8 and Pcl10. Mol Cell Biol 18(6):3289-99 SGD PMID 9584169
  5. Ni HT and LaPorte DC (1995) Response of a yeast glycogen synthase gene to stress. Mol Microbiol 16(6):1197-205 SGD PMID 8577253
  6. Parrou JL, et al. (1999) Dynamic responses of reserve carbohydrate metabolism under carbon and nitrogen limitations in Saccharomyces cerevisiae. Yeast 15(3):191-203 SGD PMID 10077186
  7. Peng ZY, et al. (1990) Purification and characterization of glycogen synthase from a glycogen-deficient strain of Saccharomyces cerevisiae. J Biol Chem 265(23):13871-7 SGD PMID 2116410
  8. Wu X, et al. (2001) Characterization of Gac1p, a regulatory subunit of protein phosphatase type I involved in glycogen accumulation in Saccharomyces cerevisiae. Mol Genet Genomics 265(4):622-35 SGD PMID 11459182
  9. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  10. submitted by Viktor Boer on 2003-07-25

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