YLL031C

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Systematic name YLL031C
Gene name GPI13
Aliases MPC1
Feature type ORF, Verified
Coordinates Chr XII:80205..77152
Primary SGDID S000003954


Description of YLL031C: ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein[1][2]




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References

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  1. Flury I, et al. (2000) YLL031c belongs to a novel family of membrane proteins involved in the transfer of ethanolaminephosphate onto the core structure of glycosylphosphatidylinositol anchors in yeast. J Biol Chem 275(32):24458-65 SGD PMID 10823837
  2. Taron CH, et al. (2000) Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose. Mol Biol Cell 11(5):1611-30 SGD PMID 10793139

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