YLL009C

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Systematic name YLL009C
Gene name COX17
Aliases
Feature type ORF, Verified
Coordinates Chr XII:131414..131205
Primary SGDID S000003932


Description of YLL009C: Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs[1][2][3][4][5]




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References

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  1. Beers J, et al. (1997) Purification, characterization, and localization of yeast Cox17p, a mitochondrial copper shuttle. J Biol Chem 272(52):33191-6 SGD PMID 9407107
  2. Heaton D, et al. (2000) Mutational analysis of the mitochondrial copper metallochaperone Cox17. J Biol Chem 275(48):37582-7 SGD PMID 10970896
  3. Horng YC, et al. (2004) Specific copper transfer from the Cox17 metallochaperone to both Sco1 and Cox11 in the assembly of yeast cytochrome C oxidase. J Biol Chem 279(34):35334-40 SGD PMID 15199057
  4. Longen S, et al. (2009) Systematic analysis of the twin cx(9)c protein family. J Mol Biol 393(2):356-68 SGD PMID 19703468
  5. Maxfield AB, et al. (2004) Cox17 is functional when tethered to the mitochondrial inner membrane. J Biol Chem 279(7):5072-80 SGD PMID 14615477

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