YKR090W

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Systematic name YKR090W
Gene name PXL1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:608946..611066
Primary SGDID S000001798


Description of YKR090W: LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin[1]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [3]





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References

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  1. Mackin NA, et al. (2004) The PXL1 gene of Saccharomyces cerevisiae encodes a paxillin-like protein functioning in polarized cell growth. Mol Biol Cell 15(4):1904-17 SGD PMID 14767053
  2. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  3. submitted by Jeff Ubersax on 2004-01-29

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