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Systematic name YKR056W
Gene name TRM2
Aliases NUC2, NUD1, RNC1
Feature type ORF, Verified
Coordinates Chr XI:549448..551367
Primary SGDID S000001764

Description of YKR056W: tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair[1][2][3]


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  1. Choudhury SA, et al. (2007) Functional and genetic analysis of the Saccharomyces cerevisiae RNC1/TRM2: evidences for its involvement in DNA double-strand break repair. Mol Cell Biochem 300(1-2):215-26 SGD PMID 17205207
  2. Johansson MJ and Bystrom AS (2002) Dual function of the tRNA(m(5)U54)methyltransferase in tRNA maturation. RNA 8(3):324-35 SGD PMID 12003492
  3. Nordlund ME, et al. (2000) Identification of the TRM2 gene encoding the tRNA(m5U54)methyltransferase of Saccharomyces cerevisiae. RNA 6(6):844-60 SGD PMID 10864043

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