YKL213C

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Systematic name YKL213C
Gene name DOA1
Aliases UFD3, ZZZ4
Feature type ORF, Verified
Coordinates Chr XI:34107..31960
Primary SGDID S000001696


Description of YKL213C: WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase[1][2][3]




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References

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  1. Ghislain M, et al. (1996) Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae. EMBO J 15(18):4884-99 SGD PMID 8890162
  2. Johnson ES, et al. (1995) A proteolytic pathway that recognizes ubiquitin as a degradation signal. J Biol Chem 270(29):17442-56 SGD PMID 7615550
  3. Wilson TE (2002) A genomics-based screen for yeast mutants with an altered recombination/end-joining repair ratio. Genetics 162(2):677-88 SGD PMID 12399380

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